If you ever designed and sliced a website mockup in Photoshop running on Mac OS X then you probably faced this: you have prepared the slices and you have exported them but the result looks a bit washed out, especially on Windows. This is not a misfuction or a bug as many tend to believe; this is how things are supposed to work.

If you google it, you will come across a large number of suggestions on how to resolve it. However, just a minor subset of them are completely solid, thus providing a concrete solution.

Dave Shea on mezzoblue writes about it. Despite the fact that he briefly analyses the phenomenon not only you can get a good idea why this happens, but you can read the best solution that I have ever tried. In brief, Dave Shea suggests to convert a sRGB profile prior to the slicing.

The single disadvantage is that the layers are erased upon the conversion so make sure to save a copy first.